Authors : Madhumithra D S, Shreyas Borkar, Santosh Kondekar
DOI : 10.18231/j.ijmpo.2020.031
Volume : 6
Issue : 3
Year : 2020
Page No : 136-138
Introduction: Amikacin is an aminoglycoside used in the treatment of a wide variety of infections. It has the broadest spectrum of action amongst the aminoglycosides. It is often associated with dire side effects like nephrotoxicity and ototoxicty. The recommended dose for Amikacin is 15 mg/kg per day as a single dose.
An 8 month infant was exposed to 10 times the normal amikacin dose. No treatment was given. Later on, no side effects were observed either.
Previously overdoses like that observed in the above case have occurred. Those cases were immediately treated as opposed to our case and no further sequelae were observed in any of those cases either. There seems to be enough reason to doubt the need for immediate treatment in the case of amikacin overdose, instead, careful observation seems to be more appropriate.
Keywords: Amikacin, Overdose, Children, Nephrotoxicity, Ototoxicity.