Serum and salivary alkaline phosphatase levels in oral health and disease: A brief review

Alkaline phosphatase is an intracellular hydrolase enzyme participating in the metabolic processes of
cells. The enzyme alkaline phosphatase (AP) occurs in many organisms ranging from bacteria to man.
Alkaline phosphatase levels were increased in various disease processes like periodontitis, gingivitis, and
bone disorders. The alkaline phosphatase enzyme released in secretions like the serum, saliva, and gingival
crevicular fluid. The serum and salivary levels were used as a diagnostic aid in oral diseases. 1 The below
was a brief review of the alkaline phosphatase levels both in serum and saliva.

Keywords: Saliva, Serum, Alkaline phosphatase.