Authors : Vinu Sugathan, Latha K Abraham, Sunitha Thomas, V P Paily, Susan John
DOI : 10.18231/j.ijpo.2020.131
Volume : 7
Issue : 4
Year : 2020
Page No : 665-668
Primary malignant melanoma of the vagina accounts for less than 0.3% of all melanomas and approximately 4% of vaginal malignancies. We present a case of a 61-year-old female who presented with complaints of difficulty in urination and a polyp arising from the vagina. Local examination showed
a polyp arising from the lateral vaginal wall and a hymenal tag. Histopathological examination of the polyp showed a neoplasm simulating a leomorphic sarcoma. The hymenal tag showed classical features of malignant melanoma. Immunohistochemistry with S100 and HMB45 confirmed malignant melanoma in the vaginal polyp. We report this case, on account of its rarity and unusual phenotypic profile, which may lead to a delayed or alternate diagnosis. Primary malignant melanoma of the vagina needs early accurate diagnosis and management due to its aggressive nature.
Keywords: Vaginal melanoma, Mucosal melanoma, Vaginal polyp, Sarcomatous polyp.