Granulocytic sarcoma presenting as a palpable breast lump in a 13-year-old female as a relapse of AML

Authors : Toyaja Jadhav, Ganesh Pendkur, Puneet Baveja

DOI : 10.18231/j.ijpo.2020.132

Volume : 7

Issue : 4

Year : 2020

Page No : 669-673

Granulocytic sarcoma, also known as myeloid sarcoma or chloroma, is a neoplasm of the myeloid cells that can arise before, concurrent with or following haematolymphoid malignancies, mostly associated with Acute Myeloid Leukaemia (AML). It is an uncommon extramedullary manifestation of AML. We report the case of a 13-year-old girl who presented with a painless lump in her breast. Her past medical history revealed AML, treated and considered in remission. A biopsy was performed in the palpable mass and the histopathological findings were consistent with a Granulocytic sarcoma of the breast, which was considered as a relapse of AML.

Keywords: Acute myeloid leukaemia, Granulocytic sarcoma, Myeloid sarcoma, t(8;21), CD56, CD99

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