Anti-NMDAR encephalitis presenting with early and prominent orolingual dyskinesia and its association with ovarian serous cystadenoma- case report

Authors : Sudhakar Pandey, Nomal Chandra Borah, Shabnam A. Ahmed, Manjari Dwivedi

DOI : 10.18231/j.ijn.2020.061

Volume : 6

Issue : 4

Year : 2020

Page No : 333-336

Autoimmune encephalitis is relatively a new entity. Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is one of the most common and well studied autoimmune encephalitis. We report a case of anti-NMDAR encephalitis presenting initially with orolingual dyskinesia and its association with large ovarian serous cystadenoma. She was given complete course of intravenous immunoglobulin (2GM/KG) as well as removal of the tumor. Histopathology of the cystic lesion revealed serous cystadenoma of the ovary. The patient is now on regular follow up and is doing well. To best of our knowledge, this is the first case in literature showing association of anti-NMDAR encephalitis with serous cystadenoma of ovary and orolingual dyskinesia as initial clinical presentation.

Keywords: AntiNMDAR encephalitis, Intravenous immunoglobulin (IVIG), Serous cystadenoma of ovary.


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