A prospective study to evaluate the repigmentation in vitiligo after noncultured epidermal cell transplant followed by puva

Authors : Mohammed Azharudeen, P K Kaviarasan, Kannambal K, Poorana B, Abhirami C

DOI : 10.18231/j.ijced.2020.065

Volume : 6

Issue : 4

Year : 2020

Page No : 325-327

Aim of the study: To evaluate the repigmentation with non-cultured epidermal cell suspension followed by PUVA in patients with stable vitiligo.
Materials and Methods: A prospective study conducted at the department of Dermatology, Venerology, Leprosy of Rajah Muthiah Medical College and Hospital. 26 cases of stable vitiligo were treated with non-cultured epidermal cell suspension followed by PUVA and were reviewed for a period of 20 weeks. 
Results: The results were assessed subjectively. 9 (34.6%) patients showed excellent response to our therapy, 7 (26.9%) patients had good response, 5 (19.3%) patients showed fair response and 3 (11.5%) showed very poor response. 17 (65%) patients showed a very good colour match when compared with the surrounding skin and 1 (3.8%) patients showed donor site scarring.
Conclusion: Epidermal non cultured cell suspension followed by PUVA is a relatively safe method with superior quality of repigmentation.

Keywords: Noncultured epidermal cell suspension, Vitiligo, Phototherapy, Hyperpigmentation.


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