Carcinoma of unknown primary: Extensive search for the culprit-A rare case entity

Authors : Dhiraj B Nikumbh, Dhiraj B Nikumbh, Parvez Mujawar, Parvez Mujawar, Roopali D Nikumbh, Roopali D Nikumbh

DOI : 10.18231/j.achr.2020.073

Volume : 5

Issue : 4

Year : 2020

Page No : 331-333

Carcinoma of unknown primary (CUP) is commonly known as ‘occult primary cancer’. It’s defined as metastatic malignant cancer confined by pathology in absence of clinically detectable, anatomically defined primary tumor site after an adequate pretreatment diagnostic evaluation.
Herein we present a case of 35 year old female of CUP presented with pain in left axillary region that is vague clinical manifestation. Histopathologically it was proved as metastatic adenocarcinoma on axillary mass probably of breast origin. Primary nature is not diagnosed even on IHC.
The aim of this case report is to highlight role of ancillary pathology techniques in challenging cases like CUP.

Keywords: Occult, Immunohistochemistry, Carcinoma, Unknown origin.


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