Occurrence and pattern of Hepatitis-A among patients with suggestive symptoms of hepatitis

Authors : Sunil Gautam, Sudhir Singh, Amit Mishra, Umar Farooq, Vasundhara Sharma, Shweta R Sharma, Imran Ahamad, Sana Nudrat, Shivendra Mohan

DOI : 10.18231/j.ijmmtd.2021.009

Volume : 7

Issue : 1

Year : 2021

Page No : 37-40

Introduction: Viral hepatitis is a systemic disorder with primary inflammation in the liver. Till now, the hepatitis are of six types i.e. A, B, C, D, E and G in which hepatitis-B is a DNA virus and (A, C, D, E and G) place RNA virus. Hepatitis viruses can cause an acute disease with symptoms including reduced appetite, muscle or joint pain, fever, nausea with yellowish discoloration of human body and eyes (jaundice) and dark urine (bilirubinuria).
The most clinically symptoms of HAV infection are dark golden-brown urine, fatigue, malaise, loss of appetite, nausea and vomiting. HAV a positive-strand RNA viruses, is stable at moderate temperature and low pH allowing the virus to survive in the environment and be transmitted by the fecal-oral route. 
Aim: Occurrence and pattern of hepatitis-A among patients with suggestive symptoms of hepatitis. 
Objectives: 1. To determines the frequency of Hepatitis-A virus infection. 2. To determine the pattern of Hepatitis-A infection in different Age group.
Materials and Methods: 5ml blood was collected from anterior cubital vein by Venipuncture from recruited patient. Samples were collected after proper consent and aseptic precautions. Then every blood sample was transfer overhead a tagged tube plane vial.
Result: The study was conducted in Department of Microbiology, Teerthanker Mahaveer Hospital. Blood sample from 87 patients including both male and female were collected from various department of the Hospital for the analysis purpose. Out of them, 10 (11.50%) cases were Hepatitis-A virus positive and 77 (88.50%) cases were Hepatitis-A virus negative.
Conclusion: The results of our study put up valuable information and connection in Hepatitis-A positive cases. Females 6 (60%) were more affected by the Hepatitis-A virus infection as compare to Males 4 (40%). An important preventive measure is the screening for Hepatitis-A Virus in blood donors. Hepatitis-A Virus infection can also be prevented by using fresh food and water, Oral-anal sex. 

Keywords: HepatitisA Virus, Primary inflammation in the liver, Blood Sample.

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