Seizure epilepsy genesis and epileptogenic nodes in epileptic patients: A procedure

Authors : V Rama Raju, V Rama Raju, V Malsoru, V Malsoru, K Srinivas, K Srinivas, B. Kavitha Rani, B. Kavitha Rani, G Madhukar, G Madhukar

DOI : 10.18231/j.ijn.2022.049

Volume : 8

Issue : 4

Year : 2022

Page No : 248-253

In this study we attempted to design, develop and substantiate a modern contemporary biomarker for epileptic (epilepsy) subjects (patients) neuronal-instability. Initial study is done on 91 subjects through the application of neuronal-unpredictability and/or variability of the marked e-SoZ as a metric to envisage and foresee the epileptic operational (surgical) outcome. the neural-instability predict (42/45) subjects unsuccess with surgery, by a total accuracy of 75% (predictive) when matched with subjective-clinicians accuracy at 49%(results-effective). We differentiate instable zonal areas (zones) which were not diagnosed in unsuccessful cases (i.e., unsuccessful outcomes). While compared with EEG features, the neural-variability outpaced in prognosis strength and, also construal, which support that neuronal delicacy as a bio-marker for the electro encephalography e-SoZ.
 

Keywords: Epilepsy, Seizure, Epileptic­seizures, E­seizures, Dynamical systems, Delicate nodes, Fragile­ nodes, Epileptic seizure onset zone, e­SoZ


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