Vision improvement after trans-sphenoidal resection of pituitary macroadenoma

Authors : Sumit Prinja, Varun Aggarwal, Ramandeep Singh, Bhumika Trivedi, Dipesh

DOI : 10.18231/j.ijashnb.2021.008

Volume : 7

Issue : 1

Year : 2021

Page No : 39-41

Introduction: Pituitary adenomas are tumours that occur in the Pituitary gland. Depending on the size it can be divided into Microadenoma (<10mm>10mm). It can present with endocrine manifestations secondary to hypo or hyper function of pituitary gland and ophthalmological manifestations due to mass effect.
Case Report: A 36-year-old female was admitted to our institution with complaints of loss of vision of right eye, headache and amenorrhea for 3 months, which were progressive in nature. Her MRI Scan revealed a well-defined sellar mass, measuring 27 x 23.18 mm, with suprasellar extension, causing expansion of pituitary fossa and superiorly extending into Hypothalamus with mild compression over optic chiasma. Prolactin level was 72.16 ng/ml. Surgery was done under general anesthesias, by Endoscopic assisted transsphenoidal approach. The adenoma was completely removed. Sella opening was closed by synthetic graft.
On awakening from anesthesias visual acuity in right eye was immediately and completely restored.
Conclusion: Pituitary adenoma is a complex set of benign tumours that present with hypersecretory syndrome and mass effect. An appropriate imaging of pituitary region using MRI and endocrinological consultation is the standard for detection of pituitary adenoma. Although, medical management and radiotherapy offer effective treatment for these tumours in specific situations, Endoscopic Trans-sphenoidal approach continues to provide optimal outcomes with low incidence of morbidity.

Keywords: Pituitary macroadenoma, Vision loss, TransSphenoidal resection.


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