Anti-D alloimmunization after platelet transfusion

Authors : Ripal J Shah, Ripal J Shah

DOI : 10.18231/j.ijpo.2021.060

Volume : 8

Issue : 2

Year : 2021

Page No : 306-308

Human platelets do not express any antigens of the Rhesus system. However, platelet concentrates contain the variable volume of contaminating RBCs, which may induce RhD alloimmunization when transfused in a RhD negative subject. Though low rate of anti-D alloimmunization related to platelet transfusion, the development of RhD and non-RhD antibodies cannot be ignored. Thus, transfusion practices could allow the transfusion of RhD positive platelet units to RhD negative patients, with the exception of females of childbearing age.

Keywords: Platelet, Transfusion, Alloimmunization, Donor, Antibody, Antigen.


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