Spectrum of esophageal lesions- A study of endoscopic biopsies

Authors : Vidya Kedarisetty

DOI : 10.18231/j.jdpo.2021.027

Volume : 6

Issue : 2

Year : 2021

Page No : 127-131

Introduction: Endoscopic biopsies is a very common outpatient procedure in gastroenterology unit. The present article is a study of endoscopic biopsies taken from the esophagus. The gastrointestinal tract cannot be visualized directly and endoscopy is a very important and easy tool for visualization of GI tract lesions directly and helping in the diagnosis in the early stage, there by helping in the overall well being of the patient.
Objectives: To emphasize the utility of endoscopic biopsies in the diagnosis of esophageal lesions. To correlate the endoscopic findings with pathological diagnosis. To study the various pathologies. 
Materials and Methods: Endoscopic biopsies taken from the esophagus were studied and analysed in the present study. The biopsies are taken by the gastroenterologist. The biopsies are fixed in 10% formalin. After fixation the biopsy specimen is processed and embedded in paraffin.4 to 5 microns thick sections were cut, stained with Haematoxylin & Eosin and studied.
Results: Out of the 118 cases of esophageal biopsies received at the Department of Pathology, Mediciti Institute of Medical Sciences from December 2016 to November, 2018. ,50 were non neoplastic lesions, 68 cases were neoplastic lesions, 50 were non neoplastic lesions, 68 cases were neoplastic lesions. Chronic non specific esophagitis was the commonest non neoplastic esophageal lesion. Squamous cell carcinoma was the commonest neoplastic lesion. The lower one third is the commonest site of pathology for esophagus. Males are mostly effected and predominant age of presentation is around 40-60 years for non neoplastic lesion and 50-70 years for neoplastic region.

Keywords: Chronic nonspecific esophagitis, Endoscopic biopsies, Esophagus squamous cell carcinoma.


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