Authors : A.G. Nerkar, A.G. Nerkar
DOI : 10.18231/j.ctppc.2021.010
Volume : 3
Issue : 4
Year : 2021
Page No : 35-37
Osteosarcoma (OS) is a type of cancer with onset in late childhood and peak at early adolescence. OS is a typically is chemo sensitive cancer. The treatment modalities include neo-adjuvant and adjuvant therapies with definitive surgery. Permutations and combinations of chemotherapeutics agents have been used. However, in many clinical trial high dose methotrexate has been used as main drug with cisplatin and doxorubicin (MAP). In recent years, case studies have cited addition of fourth drug to the three drug regimen gives a detail of drug regimen being used over past years and discusses the successful treatment.
Keywords: Methotrexate, Ifosfamide, Cisplatin