Co-infection of mucormycosis and aspergillosis in post COVID-19 patient: A concerning rare case report during second wave of COVID-19 pandemic

Authors : Vikramjeet Singh, Anupam Das, Nikhil Gupta, Ashish Chandra Agarwal, Tushar Gautam, Nikhil Raj, Jaya Garg, Manodeep Sen, Jyotsna Agarwal

DOI : 10.18231/j.ijmmtd.2021.062

Volume : 7

Issue : 4

Year : 2021

Page No : 300-303

COVID-19 manifestations have been evolving and affect different parts of the body every time a new wave comes. Association of mucormycosis in COVID-19, Covid Associated Mucormycosis (CAM) affected patients especially affecting paranasal sinuses must be given serious and timely consideration. Prolonged history of uncontrolled diabetes and over the counter use of steroids and abrupt stoppage of steroids are two main factors aggravating the illness, and both these factors must be critically checked. Clinical condition like Mucormycosis are caused by pathogenic moulds of family Mucorales and Aspergillosis is caused by Aspergillus species and both can cause an invasive disease with high case fatality rate, especially in immunosuppressed patients. In the present study we are discussing a case of co-infection in Post COVID-19 patient affected with mucormycosis and aspergillosis. A 55-year-old male patient with Type 2 diabetes mellitus presented post covid with ptosis and diplopia. Mixed infections of Rhizopus arrhizus and Aspergillus flavus were diagnosed by means of fungal microscopy and culture from biopsy sample. Treatment with Amphotericin B was started, the patient responded clinically within 15 days.
 

Keywords: Post COVID­19, Aspergillosis, diabetes mellitus, immunocompromised, mucormycosis, steroids


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