Authors : A O Okezie, C O Edeogu, D A Onweh, E C Ogbodo, A A Okebalama, E C O Izuchukwu, G A Aikpitanyi-Iduitua, D E Nwanguma, N S Nduka
DOI : 10.18231/j.ijor.2021.016
Volume : 7
Issue : 2
Year : 2021
Page No : 71-75
Background/Aim of study: The monitoring of bone fractured healing using Alkaline phosphatase, calcium ion and inorganic phosphate was evaluated among patients with fractured bone in two different centers, Alex Ekwueme Federal University Teaching Hospital Abakaliki and Bone Setters Home, Onueke, Ezza in Ebonyi State between August 2017 and September 2018.
Materials and Methods : A total of 90 adults patients from 18 years to 78 years were examined using phenolphthalein monophosphate colorimetric end point method. Out of the 90 patients, 30 were healthy normal subjects, another 30 were patients in AE-FUTHA while the remaining 30 patients were in bone setter home.
Results : Patients without bone fracture had the least mean serum level of alkaline phosphatase, 28.5 ± 9.0µl followed by those admitted in bone setter home with a mean serum level of 38.2±17.9µl while patients admitted in AE-FUTHA had the highest mean serum level of 41.4±6.5µl (P<0> Conclusion : Out of the three parameters examined, alkaline phosphatase test was more precise, reliable and patient doctor friendly; hence it can be used as a veritable tool to monitor the process of bone fracture healing effectively.
Keywords: Fracture, Bone setters, Healing, ALP, Calcium ion, Inorganic phosphate