Orthokeratinized Odontogenic Cyst: A Case Series with Clinicopathologic Variation

Authors : Mandakini Mandale, Vaishnavi Marge, Jayanti Humbe, Vaishali Nandkhedkar, Savita Wagh, Monika Kajalkar

DOI : 10.9734/ijrrd/2025/v8i2231

Volume : 8

Issue : 2

Year : 2025

Page No : 278-285

Orthokeratinized Odontogenic Cyst (OOC) is a rare developmental odontogenic cyst, accounting for approximately 1% of all odontogenic cysts and 10% of all keratinizing odontogenic jaw cysts. The 2017 WHO classification considered OOC as a distinct entity. It is characterized by an Orthokeratinized stratified squamous epithelial lining, a benign nature, and a low recurrence rate of less than 2%. Unlike OKC, OOC lacks aggressive behaviour, showing minimal proliferative activity. Radiologically, OOCs often present with buccolingual expansion and cortical bone destruction, but their growth pattern is less invasive than that of OKC. Due to its favourable prognosis and low recurrence, OOCs should be differentiated from OKC for its appropriate diagnosis & management.


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