MICROBES MATTER: A REVIEW ON THE CURRENT UPDATES OF GUT MICROBIOTA IN RELATION TO AUTISM

Authors : Ansar Ahmad Paray * 1, Mohsin Amin Mir 2, Mahesh Chandra 1, Aasim Yousuf 2, Manju Singh 1 and Jyotsna Devgon

DOI : 10.13040/IJPSR.0975-8232.16(2).345-53

Volume : 16

Issue : 2

Year : 2025

Page No : 345-53

Microbiota, in simple terms means the community ofmicroorganisms, whereas microbiome means the whole genomes of themicroorganisms in a particular environment. We humans consist of a largemicrobiome within as well as on body, most in the gut. The gut microbiota in humanplays significant role in different aspects such as in human metabolism, nutrition,physiology, immune function, and various other body functions. The microbiota ofhuman gut is mainly composed of strict anaerobes, outnumbering the facultativeanaerobes. Evidence from various studies across the globe has reported that autisticpeople carry an altered gut microbiota in comparison to normal people, influencingthe immune system thus establishing an relation between dysbiotic gut microbiotawith autism. Moreover, as far as antibiotics are concerned, their irrigational usebedsides having the association with antimicrobial resistance are also associated withthe autism spectrum disorder development when used in pregnancy and earlychildhood as reported by studies. Keeping the objective in mind, this review waswritten to highlight the present existing knowledge regarding gut human microbiotaand its relation with development of autism and also the effect of using antibiotics inmaternal life and their role in development of autism in children’s (PDF) MICROBES MATTER: A REVIEW ON THE CURRENT UPDATES OF GUT MICROBIOTA IN RELATION TO AUTISM. Available from: https://www.researchgate.net/publication/388779787_MICROBES_MATTER_A_REVIEW_ON_THE_CURRENT_UPDATES_OF_GUT_MICROBIOTA_IN_RELATION_TO_AUTISM [accessed Feb 17 2026].


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