Aggressive renal myxoid liposarcoma with co-existing bilateral benign angiomyolipoma: A rare case report

Authors : Dhivya Nanjundamoorthi, Shobhanaa PS, Annapurneswari Subramanium

DOI : 10.18231/j.ijpo.2025.044

Volume : 12

Issue : 2

Year : 2025

Page No : 218-223

This report describes a 71-year-old male with Primary renal myxoid liposarcoma (MLPS), who presented with left loin pain and mass per abdomen. Computed Tomography (CT) revealed a complex mass in the left kidney with a right renal angiomyolipoma. There were two distinct lesions on gross examination. Histopathology, Immunohistochemistry (IHC) and Fluorescence in situ hybridization (FISH) of larger tumour were consistent with Myxoid Liposarcoma, while the smaller tumour was Angiomyolipoma. The patient decided to forgo chemotherapy, and died of disseminated metastasis. This case underscores the diagnostic challenges of rare renal neoplasms, with fewer than five Primary renal MLPS documented in literature. Keywords: Angiomyolipoma, Bilateral, Multicentric, Myxoid liposarcoma, Renal, Retroperitoneum.


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