Efficacy of Tru-cut biopsy of the cervical lymphnodes over FNAC for detecting MTB using CBNAAT histopathology and cultures

Authors : Mohammed Abdul Basith, NM Aleemuddin, Ashfaq Hasan, Fahad Abdullah, Syed Mahmood, S Adeeb Mujtaba Ali

DOI : 10.4103/jdrysruhs.jdrysruhs_32_24

Volume : 13

Issue : 3

Year : 2024

Page No : 247-252

ABSTRACT Introduction: The present study was carried out to see the usefulness of Tru-cut biopsy over fine needle aspiration (FNA) in diagnoses of tuberculosis (TB) cervical lymphadenopathy and comparing their yields by performing ZN staining, culture, cytology, histopathology, and CBNAAT. Observation and Results: It was found that the yield of Tru cut was significantly more in ZN staining and histopathology. Even though the yield was more in culture and CBNAAT also, it was not statistically significant. FNA is a popular method which is very widely used, but it has a low yield. From the results, it was inferred that for FNA, the positive rate was 27.6%, 38.4%, 67.7%, and 43% for the four modalities of ZN staining, CBNAAT, cytology, and acid-fast bacilli cultures, respectively. Comparatively, for Tru-cut biopsy, the positive rate was 36.9%, 46.2%, 92.3%, and 47.7%, respectively, in all four modalities. It was noticed that the highest value was recorded for histopathology, followed by culture and CBNAAT for Tru-cut biopsy procedures. Comparatively, FNA showed the highest negative rate for ZN staining and CBNAAT. Conclusion: The present study also highlights the importance of Tru-cut biopsy over FNA. It is one of the emerging techniques which if used properly could offer a better yield. Further results and conclusions are discussed in the paper.


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