Authors : Ashalatha. N., Kumarguru. B.N., Dayananda. B.S., A. Nagarajappa, S.L. Kuruba
DOI : 10.5580/1241
Volume : 11
Issue : 1
Year : 2010
Page No : 1-6
INTRODUCTION: Angioimmunoblastic T cell lymphoma [AITL] is an aggressive subtype of Peripheral T cell lymphoma [PTCL] characterized by systemic disease. It is a rare subtype of Non-Hodgkins lymphomas. However it forms a major subset of peripheral T cell lymphomas. Lymph node is the primary site of disease and virtually all patients present with generalized Lymphadenopathy.CASE REPORT: A 42 year old male presented with fever of short duration and a solitary axillary lymph node swelling on the right side. Systemic examination revealed moderate ascites and hepato-spleenomegaly. Haematological investigations revealed pancytopenia and abnormal liver function test. Axillary lymph node showed histological features suggesting AITL and was confirmed by a panel of immunohistochemistry [IHC].CONCLUSION: AITL presenting as solitary axillary lymph node enlargement is unusual. Such atypical presentation mandates careful clinical and laboratory evaluation. IHC is an effective ancillary tool for confirmation of diagnosis of this distinct clinicopathological entity.