Unusual Presentation Of Angioimmunoblastic T-Cell Lymphoma As A Solitary Lymph Node: A Case Report And Review Of Literature
INTRODUCTION: Angioimmunoblastic T cell lymphoma [AITL] is an aggressive subtype of Peripheral T cell lymphoma [PTCL]
characterized by systemic disease. It is a rare subtype of Non-Hodgkins lymphomas. However it forms a major subset of
peripheral T cell lymphomas. Lymph node is the primary site of disease and virtually all patients present with generalized
Lymphadenopathy.CASE REPORT: A 42 year old male presented with fever of short duration and a solitary axillary lymph node
swelling on the right side. Systemic examination revealed moderate ascites and hepato-spleenomegaly. Haematological
investigations revealed pancytopenia and abnormal liver function test. Axillary lymph node showed histological features
suggesting AITL and was confirmed by a panel of immunohistochemistry [IHC].CONCLUSION: AITL presenting as solitary
axillary lymph node enlargement is unusual. Such atypical presentation mandates careful clinical and laboratory evaluation. IHC
is an effective ancillary tool for confirmation of diagnosis of this distinct clinicopathological entity.
characterized by systemic disease. It is a rare subtype of Non-Hodgkins lymphomas. However it forms a major subset of
peripheral T cell lymphomas. Lymph node is the primary site of disease and virtually all patients present with generalized
Lymphadenopathy.CASE REPORT: A 42 year old male presented with fever of short duration and a solitary axillary lymph node
swelling on the right side. Systemic examination revealed moderate ascites and hepato-spleenomegaly. Haematological
investigations revealed pancytopenia and abnormal liver function test. Axillary lymph node showed histological features
suggesting AITL and was confirmed by a panel of immunohistochemistry [IHC].CONCLUSION: AITL presenting as solitary
axillary lymph node enlargement is unusual. Such atypical presentation mandates careful clinical and laboratory evaluation. IHC
is an effective ancillary tool for confirmation of diagnosis of this distinct clinicopathological entity.