Authors : Ashalatha.N, Dayananda. B.S, S. Kuruba, A. H. Nagarajappa, Kumarguru. B.N.
Volume : 4
Issue : 2
Year : 2010
Page No : 1-6
INTRODUCTION: Bizarre leiomyoma is infrequently encountered in surgical pathology. It is characterized by presence of multinucleated giant cells with pleomorphic nuclei and little or no mitotic activity. CASE REPORT: A 40 year old female presented with mass per abdomen of two years duration. Clinically she was diagnosed to have fibroid and total abdominal hysterectomy was performed. Grossly uterus was bulky. Cut section revealed multiple grey-white circumscribed tumor nodules with multiple tiny cysts. Microscopy showed features of bizarre leiomyoma characterized by bizarre multinucleated giant cells, moderate to severe pleomorphism and little mitotic activity. However, coagulative necrosis was absent. CONCLUSION: Bizarre leiomyoma closely mimics leiomyosarcoma. A systematicapproach is needed to arrive at the right diagnosis and thereby exclude malignancy.