Authors : Karveer Aghade, Uttara Joshi , Ashish Kandalkar , Ramdas Pandhare
Volume : 21
Issue : 7
Year : 2022
Page No : 132-143
To give scientific background to the above traditional claim, the aerial parts of Acalypha Indica Linn. were evaluated for its antilithiatic activity. In the present study, aerial parts of Acalypha Indica Linn. were subjected to morphological, microscopically, phytochemical investigations and evaluated for in vivo antilithiaticactivity. The plant material after defatting with pet. Ether (60-80) extracted with ethanol and then fractionated with chloroform, ethyl acetate and n-butanol. Qualitative chemical examination of various extracts revealed the presence of Alkaloids, Steroids, Flavonoids, Glycosides, Tannins, and Carbohydrates. Acute toxicity studies were carried out as per OECD guidelines and the doses were fixed at 200 mg/kg b.w. and 400 mg/kg b.w. The Ethanolic extract was evaluated for in vivoantilithiatic activity by using CCl4 induced antilithiatic model. The ethanolic extract showed better effect at the dose of 10 mg/kg b.w in lowering elevated level of kidney stones in the kidney.