ANTIUROLITHIATIC POTENTIAL OF Parkia biglobosa, Lannea humilis STEM BARK METHANOL EXTRACT AND KO-888 TONIC
Kidney stones affect several biological processes, including urine volume, pH, calcium oxalate, and urates.
The aim of the study was to evaluate the antiurolithiatic potential of Parkia biglobosa, Lannea humilis stem bark and
KO-888 (Jigsimur). These plants were extracted with methanol using soxhlet extraction. The phytochemical
screening was carried out using standard procedures. Renal calculi were induced using ethylene glycol in 55 rats
and treated with the extracts and KO-888 for 14 days. The phytochemical contents showed the presence of tannins,
saponins, flavonoids, steroids, hydrogen cyanides, glycosides, alkaloids, phenols, and terpenoids with copious
concentrations of glycosides, alkaloids, and terpenoids in the plant extracts. While, steroids, hydrogen cyanides,
alkaloids, and terpenoids were absent in K0-888 compared to the plant extracts. The MDA level decreased
significantly (p
The aim of the study was to evaluate the antiurolithiatic potential of Parkia biglobosa, Lannea humilis stem bark and
KO-888 (Jigsimur). These plants were extracted with methanol using soxhlet extraction. The phytochemical
screening was carried out using standard procedures. Renal calculi were induced using ethylene glycol in 55 rats
and treated with the extracts and KO-888 for 14 days. The phytochemical contents showed the presence of tannins,
saponins, flavonoids, steroids, hydrogen cyanides, glycosides, alkaloids, phenols, and terpenoids with copious
concentrations of glycosides, alkaloids, and terpenoids in the plant extracts. While, steroids, hydrogen cyanides,
alkaloids, and terpenoids were absent in K0-888 compared to the plant extracts. The MDA level decreased
significantly (p