Authors : Suresh Chari, Madhur Gupta, Sunita Ghike
Volume : 26
Issue : 1
Year : 2011
Page No : 1-5
Preeclampsia is a frequent and potentially dangerous complication of pregnancy. A case control study was carried out to assess the levels of homocysteine, lipid peroxidation marker malondialdehyde (MDA) and antioxidant enzymes glutathione peroxidase (GPx) and superoxide dismutase (SOD) in patients with preeclampsia. The levels of malondialdehyde and homocysteine was significantly increased in patients with preeclampsia (p<0.001). The levels of GPx and SOD were significantly increased in patients with preeclampsia (p<0.001).Levels of homocysteine correlated positively with the levels of MDA and negatively with GPx and SOD. Oxidative stress may thus be a possible link in between homocysteine and preeclampsia. Copyright of Journal of Recent Advances in Applied Sciences is the property of Evoker Research Perfecting Company and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.