Authors : Madhur Gupta, Suresh Chari, Abhay Kolte, Manju Chandankhede
Volume : 2
Issue : 24
Year : 2013
Page No : 4325-4328
ABSTRACT: Periodontitis is a chronic condition leading to the destruction of the periodontium. A case control study was carried out in 30 subjects with chronic periodontitis aged 30-65 years (group II) and age matched with 30 control subjects (group I). Salivary and serum malondialdehyde, which is a marker of lipid peroxidation, was estimated in the cases and controls. Salivary MDA was elevated (p<0.001) in patients with chronic periodontitis there was no change in serum MDA levels when compared with normal controls. Increased levels in MDA may be closely associated with periodontal disease and salivary estimation may provide advantage in pathogenesis of the periodontal disease.