Authors : Jose Thomas, Lakshmanan , Deeshma
DOI : 10.18231/j.jsas.2023.010
Volume : 5
Issue : 2
Year : 2023
Page No : 39-45
Aims & Objectives: The aim of the study is to assess the clinical profile of patients undergoing thyroidectomy and to determine its association with FNAC (fine needle aspiration cytology) and histopathological report; and to compile a statistical data on the percentage of various malignancies and benign conditions of thyroid in patients undergoing thyroidectomy.
Materials and Methods: This was a prospective study conducted in a rural tertiary care centre among the patients undergoing thyroidectomy. Minimum sample size was estimated to be 110. Convenience sampling technique was adopted and data was collected using pretested semi-structured questionnaire with the help of interviews, clinical examinations and investigation reports. Data was analyzed using SPSS trial v25.
Results: Mean age of those who underwent thyroidectomy was 44.81 years. 96% were females. Most common clinical diagnosis was multinodular goiter (80%). Malignancies constituted 4%. Most common diagnosis as per FNAC was Colloid goiter (73%). There was statistically significant association of clinical diagnosis with, FNAC findings and with postoperative histopathological examination. As per the present study, efficacy of FNAC to differentiate malignant lesions was 100%.
Conclusion: Most common malignancies were: Papillary Ca and Follicular Ca. Among benign lesions, colloid goiter was most common. Clinically, 4% thyroid cases were identified as malignancies, which were consistent with findings of FNAC and post-operative HPE reports. With efficacy of 100% in the present study, FNAC stands as an important premanagement investigation; hence the study recommends FNAC mandatorily with or without other investigation such as radiological features.
Keywords: Thyroidectomy, FNAC Thyroid, Histopathological examination of Thyroid, Thyroid malignancy, Goiter, Solitary nodule, Thyroid carcinoma, Sensitivity