The antagonistic relationship of fetuin-A and adiponectin in obese type 2 diabetes mellitus

Authors : Shailja Kurele, Jusmita Dutta, Anupama Patne

DOI : 10.18231/j.pjms.2023.097

Volume : 13

Issue : 2

Year : 2023

Page No : 521-524

Background: Fetuin-A and adiponectin display noteworthy affiliations, bolstered by recent prove, with metabolic disorder, obese type 2 diabetes including hyperglycemia, central weight and insulin resistance as the most components, but their natural capacities are inverse. The point of this consider was to confirm the role of fetuin-A and adiponectin are the touchy marker for assessment of obese type 2 diabetes.
Materials and Methods: In this analytical cross-sectional study, 100 control and patients were chosen from the physical examination database. Serum levels of fetuin-A and adiponectin were measured utilizing an enzyme-linked immunosorbent measure (ELISA) method. The Statistical software namely SAS 9.2, SPSS 15.0, Stata10.1, MedCalc 9.0.1 , Systat 12.0 and R environment ver.2.11.1 were used for the analysis of the data and Microsoft word and Excel have been used to generate graphs, tables etc.
Result: Compared with fetuin-A or adiponectin was significantly associated with obese type 2 diabetes mellitus (P < 0> Conclusions: Fetuin-A or adiponectin are antagonistic linked with each other in obese type 2 diabetes mellitus
 

Keywords: Adiponectin, Fetuin­A, Obese type 2 diabetes


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