Astudy on prognostic significance of neutrophil-lymphocyte ratio in patients with stemi

Authors : Anurekha G, Nallathambi M, Paranthakan C

DOI : 10.18231/j.pjms.2023.087

Volume : 13

Issue : 2

Year : 2023

Page No : 464-468

Introduction: Atherosclerosis, the clinically manifested form of cardiovascular disease (CVD), mainly accounts for most deaths worldwide. Inflammatory disorders that elevate CVD risk have been associated with circulating inflammatory markers that encompass neutrophil-lymphocyte ratio (NLR), which could be employed as an economical prognostic tool for the diagnosis of the same.
Aim: Hence, this study focused on assessing the extrapolative implication of NLR among ST-Elevation Myocardial Infarction (STEMI) patients.
Materials and Methods: The observational study included 55 STEMI patients (Mean age – 52.08 years) at Thanjavur medical college (December 2015 to February 2016). The patients were delineated into two groups based on NLR values (high >3.0 and low <3> Results: Among the 55 patients, the post-MI complication was observed in 44 subjects, among which 10% of them expressed a high NLR value. A notable proportion of patients displaying arrhythmia and LV dysfunction had higher NLR values.
Conclusion: Henceforth, the study reveals the independent and vital prognostic association between NLR and atherosclerosis that could be designated as a reliable marker in the early diagnosis of the disease as well post MI complications.


Keywords : Atherosclerosis, Inflammatory markers, arrhythmia, LV dysfunction, Post­MI complications


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