Central odontogenic fibroma: A case report

The central odontogenic fibroma (COF) is a rare benign odontogenic mesenchymal tumour of jaw bone derived from the odontogenic ectomesenchyme. It is characterized by a fibrous mature stroma with variable number of strands or islands of inactive-looking odontogenic epithelium. The presented case is a 46 years old male complaining of asymptomatic mandibular bony swelling. Radiographically, the lesion is unilocular radiolucent, with root resorption and displacement of teeth. Histopathology showed dense fibrous connective tissue stroma, loosely arranged with spindle and stellate-shaped mesenchymal cells, inactive odontogenic epithelium island and osteoid tissue. In this case report, we also discuss about the types, pathogenesis, and recent concepts regarding COF.


Keywords: Odontogenic tumors, Central odontogenic fibroma, Oral tumours