Authors : Kaina Bhonsle*, Alka Vyas, Harish Vyas
DOI : 10.18231/j.ijmmtd.2023.022
Volume : 9
Issue : 2
Year : 2023
Page No : 116-120
Objectives: At present, resistance of uropathogenic bacteria towards different antibiotics is increasing worldwide due to improper, nonspecific and uncontrolled use of antibiotics; hence the treatment of UTI becomes difficult. These resistant uropathogens are major cause of increased rate of morbidity and mortality. This study was conducted to investigate frequency of causal bacterial agents of UTI and their antibiotics susceptibility pattern.
Materials and Methods: The present study was conducted on total 770 urine samples from suspected patients of urinary tract infections, these samples were collected over the period of one year November 2018- October 2019 from different hospitals of Ujjain. Uropathogens were isolated and identified from collected urine sample by biochemical tests and their susceptibility pattern was studied against different antibiotics by Kirby Bauer Disc Diffusion method.
Results: A total of 770 urine samples were collected among which 486 (63.1%) samples were tested positive for urinary tract infection in their analysis and prevalence was found higher in female patients (71.6%) as compare to male patients (28.4%). The most common isolated uropathogens were (45.6%), (27.1%), (15.6%), (7.4%) and (4.1%).These isolated uropathogens were highly susceptible to Doripenem, Meropenem, Imepenem, Gentamicin, Piperacillin/Tazobactam, Vancomycin, Linezolid and Rifampin.
Conclusion: Due to high prevalence of uropathogens and increased rate of resistance among uropathogens, continued surveillance on uropathogens and their resistance is needed for its proper treatment. So the choice of drug for the treatment of urinary tract infections becomes narrow and its treatment is based on local antimicrobial sensitivity of uropathogens to prevent treatment failure and misuse of antibiotics.
Keywords: Antibiotics, Bacteria, Uropathogens, Prevalence, Susceptible, Urinary Tract Infection