Transformation of commensal to a pathogen: Blood stream infection due to coagulase negative staphylococci among patients attending tertiary care hospital in North India

Authors : Vikramjeet Singh, Pranshu Pandey, Anupam Das*, Manodeep Sen, Jyotsna Agarwal


Volume : 7

Issue : 2

Year : 2021

Page No : 71-76

Aims and Objectives: Aim of this study was to know the prevalence of Coagulase Negative Staphylococci (CoNS) in Blood Stream Infection (BSI) among patients attending a Superspeciality hospital in North India. Objective of this study was to compare incidence of CoNS in ICU and ward patients suffering from BSI and their antimicrobial susceptibility pattern. Materials and Methods: This retrospective hospital based study was conducted in the Microbiology Department, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow for a period of two years (January, 2017 -December, 2018). Blood samples from a total of 6498 patients from Out-Patient, In-Patient and Intensive care unit departments were subjected to aerobic and anaerobic bacterial culture. Culture positive broth was subcultured on Blood Agar and MacConkey Agar to isolate pathogens in pure culture. Pure cultured isolates were tested for antimicrobial susceptibility pattern by Kirby Bauer Disk Diffusion method as per CLSI 2018.