In vitro evaluation of biological activities of aqueous extract of Sida cordifolia

Authors : Fahima Majeed, Anjana J C

DOI : 10.18231/j.ijmr.2022.022

Volume : 9

Issue : 2

Year : 2022

Page No : 124-130

Introduction: Herbs are making a comeback, and the herbal renaissance is taking place all over the world. Medicinal plants continue to play an essential role in developing and emerging countries. Considering the chemical and therapeutic elements obtained in natural form from plants and plant extracts, they play an essential role in modern medicine.
Materials and Methods: The present study aims to evaluate the phytochemicals, antimicrobial and anti-inflammatory activity of the aqueous extract of .
Results: The phytochemical examination revealed the presence of alkaloids, steroids, coumarins, and glycosides in the root's aqueous extract. The antimicrobial activity against the Gram-negative organisms (that cause urinary and secondary infections) was performed. The aqueous extract showed maximum activity against sp with a zone of inhibition of 28 mm and an almost similar zone size was measured against antibiotics Ciprofloxacin. The anti-inflammatory tests were also performed and the extract exhibited an appreciable presence of anti-inflammatory metabolites.
Conclusion: The test extracts inhibited protein (albumin) denaturation in a concentration-dependent manner, according to the current data. Secondary metabolites comprise a vast number of functional moieties that interact to create a broad range of biological functions. Many modern drugs are based on plants and plant-based compounds, and they are currently being used to treat various ailments.


Keywords: Phytochemicals, Antibacterial, Anti-Inflammatory, Secondary metabolites.


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