Anti-arthritic potential of jatropha curcas flowers extract using complete freund’s adjuvant (CFA)-induced arthritis model

Authors : Harshit Sharma, Megha Jha, Ragini Bundela, Sourabh Jain, Karunakar Shukla

DOI : 10.18231/j.ijcaap.2023.010

Volume : 8

Issue : 1

Year : 2023

Page No : 59-64

Jatropha curcas is a member of the euphorbiaceae family and has a number of therapeutic benefits. The anti-arthritic potential of Jatropha curcas flowers extracted using various solvents is the focus of the current investigation. The use of several antioxidant assays has been researched for qualitative and quantitative evaluation of isolated chemicals and antioxidant activity. By administering crude extract orally at dose concentrations of 200 mg/kg and 400 mg/kg to rats that had Complete Freund's adjuvant (CFA)-induced arthritis, it was possible to assess the anti-arthritic effectiveness of the chosen solvent, ethanolic extract. On the 28th day of treatment, paw volume analysis and haematological parameters were analysed. The results show that extract from Jatropha curcas flowers has a sizable anti-arthritic effect.
 

Keywords: Jatropha curcas, Anti­arthritic, Freund's adjuvant, Phytochemical estimation


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