A comprehensive review on preliminary screening models for the evaluation of anti-cancer agents

Authors : Bhargav K Kamani, Keval Y. Raval

DOI : 10.18231/j.ijcaap.2023.004

Volume : 8

Issue : 1

Year : 2023

Page No : 27-31

Cancer refers to a category of illnesses characterised by uncontrolled growth of new cells. The screening of an anticancer drug is a time-consuming procedure that requires several in-vitro, in-vivo, and clinical investigations. Toxic dosages of screening pharmaceutical drugs in-vivo at varying concentrations need to be envisioned in order to prevent chemical poisoning in animals throughout an experiment. Cancer management has been the subject of several in-vitro and in-vivo investigations. To determine the test compound's anti-cancer efficacy, this research compiled a review of in vivo and in vitro assays. Here, the study emphasizes on the numerous preclinical approaches and processes used in anticancer research.
 

Keywords: Cancer, In­vivo, in­vitro, Anti­cancer drug, Screening methods


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