Platelet rich fibrin (PRF) and its application in oral surgery: A literature review

Platelet rich fibrin (PRF) is a autogenous platelet concentrate containing growth factors and cytokines, trapped in fibrin matrix. Growth factors which are present provides ideal environment for wound healing and regeneration of the tissues. Platelet Concentrate have evolved a long way since 1954. In recent time it has been used in the field of medical science including dentistry, oral surgery, plastic surgery, orthopaedic surgery etc. This review discuss the evolution of platelet concentrate, its preparation technique and its application in the field of dentistry and oral surgery.
 

Keywords: Platelet rich fibrin (PRF), Platelet derived growth factor (PDGF), Sinus lift, Wound healing.