A rare case of malignant paraganglioma of urinary bladder

Authors : Arpita Nishal, Sejal Gamit, Priyanka Desai

DOI : 10.18231/2581-3706.2018.0011

Volume : 3

Issue : 1

Year : 0

Page No : 47-49

Paraganglioma are neuroendocrine tumors arising from extra adrenal sympathetic and Para-sympathetic nervous system,¹ either from the chromaffin positive paraganglion tissue or the chromaffin negative glomus cells² derived from the embryonic neural crest. Paraganglioma of urinary bladder is rare, accounting for approx. 0.06% of all bladder tumours.³ The majority of these tumors are benign but can occasionally show malignant behaviour.⁴ The only absolute criterion for malignancy is the presence of metastasis at sites where chromaffin tissue is not usually found. We report on a patient with a paraganglioma of urinary bladder. Although patient presented with asymptomatic hematuria and had a blood pressure of, these were appreciated after histological examination of total radical cystectomy specimen had elucidated the correct diagnosis.

Keywords: Paraganglioma, Urinary bladder, Neuroendocrine tumour

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