MRI of brain tumors - A surgeons view

Authors : Lijin J.L, John Joseph Martis, Reshmina Chandni Clara Dsouza, Elroy Saldanha, Peter Penual Joshua

DOI : 10.18231/2455-846X.2018.0006

Volume : 4

Issue : 1

Year : 0

Page No : 18-19

Introduction and Objective: There has been a steady increase in the incidence of brain lesions both benign and malignant in the rast decade as a result of the advances that have taken place in medical imaging technology.
It is also a known fact that the overall malignancy rate has increased in the past decade as a result of various factors. Unlike other areas in the body it should be remembered that the brain tissue is not directly accessible to the exterior, and localization of the lesion is difficult in the three dimension in the brain making the tissue diagnosis difficult.
With the increasing use of technology for detections at times when imaging like Computer tomography done for other conditions like vehicular accidents, headache or even at request of the patient, lesions of brain that were asymptomatic come to light.
It is the responsibility of the health personnel to see that the corrects diagnosis be done and not leave the patient and the care takers to the dilemma of the disease.
MR spectroscopy is useful in establishing the diagnosis of by demonstration of elevated choline, a metabolite that is found in the normal brain and raised in tumors due to high cell turnover. We kept all this in mind aimed at evaluating brain lesions comparing MRS with histopathology.
Materials and Methods: The study was a prospective non randomized analytical study conducted on 40 successive cases who met pre-defined criteria who had come to the radiology department of father muller medical college for MRI brain, with clinical suspicion of brain tumour or MRI detected brain tumour.
Results and Observations: In our study we found that abnormal Magnetic resonanc regions had consistently lower NAA than in normal-appearing tissue, which is consistent with the theory that NAA is found primarily in neurons, and that tumour and necrotic and reactive tissues all demonstrate an abnormally low neuronal cell density.
Conclusion: We concluded that Magnetic resonance spectroscopy could recognize regions the location and the type of tumor, also help in distinguishing them from normal tissue thus helping in guiding surgical biopsies and planning focal therapies.

Keywords: Magnetic resonance spectroscopy, Central nervous system, Brain tumor.


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