Generalized Dowling Degos disease: A rare genetic disorder

Dowling Degos disease (DDD) is an uncommon, autosomal dominant genodermatosis characterized by acquired, flexural hyperpigmentation. Clinico-histopathological correlation is diagnostic showing multiple hyperpigmented macules clinically and marked, heavily pigmented, slender and elongated rete ridges on histology. This entity needs to be differentiated from other reticulate hyperpigmentary disorders. Due to rarity of this condition, we report a case of generalized Dowling Degos disease in an adolescent female.

Keywords: Dowling Degos disease, Genodermatosis, Hyperpigmentation.