The spectrum of dengue fever in pregnancy

Authors : S. Lalitha, Padmasri R, Akhila .M.V, Anjali R

DOI : 10.18231/2394-2754.2018.0092

Volume : 5

Issue : 3

Year : 0

Page No : 399-404

Introduction: Dengue is a vector-borne disease transmitted by the mosquito Aedes aegypticus. Dengue infection in pregnancy carries the risk of hemorrhage for both the mother and the newborn.
Materials and Methods: 148 patients with acute febrile illness during Nov 2015 to Nov 2017 were analysed. Data regarding course of illness, lab reports which included complete blood count, urine routine and culture, NS1 Antigen, WIDAL and Peripheral smear for malarial parasite, treatment received, maternal and perinatal outcome were analysed from records.
Results: NS1 Antigen was detected in 40% of all cases with fever. Amongst the remaining, 15% had viral fever, 14% had urinary tract infection, 10% had enteric fever, 8% had lower respiratory tract infection, 2% had malaria and 9% had fever of unknown origin. Thrombocytopenia was present in 40% of dengue positive patients and 30% of patients required transfusion. 2 patients diagnosed close to term had postpartum hemorrhage treated with platelets and FFPs. There were two neonatal deaths.
Conclusion: Though most cases required only conservative management one has to keep in mind the correlation of period of gestation to the outcome and complications.

Keywords: Dengue, Pregnancy, Adverse effects.


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